Werkingsmechanisme
Välimäki V-V., Aro H. Molecular basis for action of bioactive glasses as bone graft substitute. Scand J Surg 2006; 95(2):95-102.
Virolainen P., Heikkilä J., Yli-Urpo A., Vuorio E., Aro H. Histomorphometric and molecular biologic comparison of bioactive glass granules and autogenous bone grafts in augmentation of bone defect healing. J Biomed Mat Res Part A, 1997, 35(1):9-17.
Orthopedie & traumatologie
Pernaa K, Koski I, Mattila K, Gullichsen E, Heikkila J, Aho A, Lindfors N. Bioactive Glass S53P4 and Autograft Bone in Treatment of Depressed Tibial Plateau Fractures - A Prospective Randomized 11-year Follow-Up. J Long Term Eff Med Implants. 2011;21(2):139-48.
Frantzén, Janek; Rantakokko, Juho; Aro, Hannu T.; Heinänen, Jyrki; Kajander, Sami; Gullichsen, Eero; Kotilainen, Esa; Lindfors, Nina C. Instrumented Spondylodesis in Degenerative Spondylolisthesis With Bioactive Glass and Autologous Bone: A Prospective 11-year Follow-up. Journal of Spinal Disorders & Techniques, Sep 2011(Epub)
Lindfors, N. Clinical Experience on Bioactive Glass S53P4 in Reconstructive Surgery in the Upper Extremity Showing Bone Remodelling, Vascularization, Cartilage Repair and Antibacterial Properties of S53P4. J Biotechnol Biomaterial 2011, 1:5.
Heikkilä J., Kukkonen J., Aho A., Moisander S., Kyyrönen T., Mattila K. Bioactive glass granules: a suitable bone substitute material in the operative treatment of depressed lateral tibial plateau fractures: a prospective, randomized 1 year follow-up study. J Mater Sci: Mater Med, 2011, 22(4): 1073-1080.
Lindfors N., Koski I., Heikkilä J., Mattila K., Aho A. A prospective randomized 14-year follow-up study of bioactive glass and autogenous bone as bone graft substitutes in benign bone tumors. J Biomed Mat Res Part B, 2010, 94B(1):157-164.
Lindfors N., Koski I., Heikkilä J., Mattila K., Aho A. Bioactive glass and autogenous bone as bone graft substitutes in benign bone tumors. J Biomed Mat Res Part B, 2009, 90(1):131-136.
Lindfors, N. Treatment of a recurrent aneurysmal bone cyst with bioactive glass in a child allows for good bone remodelling and growth. Bone, 2009, 45(2):398-400.
Lindfors N., Heikkilä J., Aho A. Long-term evaluation of blood silicon and ostecalcin in operatively treated patients with benign bone tumors using bioactive glass and autogenous bone. J Biomed Mat Res Part B, 2008, 87B(1):73-76.
Osteomyelitis
Geurts J, Chris Arts JJ, Walenkamp GH. Bone graft substitutes in active or suspected infection. Contra-indicated or not? Injury. 2011 Jul 13. [Epub ahead of print]
Lindfors N., Hyvönen P., Nyyssönen M., Kirjavainen M., Kankare J., Gullichsen E., Salo J. Bioactive glass S53P4 as bone graft substitute in treatment of osteomyelitis. Bone 2010; 47:212-218.
Cranio-maxillo-faciale en KNO
Turunen T, Peltola J, Yli-Urpo A, Happonen RP. Bioactive glass granules as a bone adjunctive material in maxillary sinus floor augmentation. Clin Oral Implants Res. 2004 Apr;15(2):135-41.
Aitasalo K., Peltola M. Bioactive glass hydroxyapatite in fronto-orbital defect reconstruction. Plast Reconstr Surg, 2007, Dec; 120(7):1963-72.
Peltola M., Aitasalo K., Suonpää J., Varpula M., Yli-Urpo A. Bioactive glass S53P4 in frontal sinus obliteration: a long-term clinical experience. Head&Neck, 2006, Vol. 28: 834-841.
Peltola M., Aitasalo K., Suonpää J., Yli-Urpo A., Laippala P., Forsback AP. Frontal sinus and skull bone defect obliteration with three synthetic bioactive materials. A comparative study. J Biomed Mat Res Part B: (Appl Biomat), 2003, 66B:364-372.
Stoor P., Pulkkinen J., Grénman R. Bioactive glass S53P4 in the filling of cavities in the mastoid cell area in surgery for chronic otitis media. Annal Otol Rhinol Laryngol. 2010 Jun;119(6):377-82.
Bacterial growth inhibition
Leppäranta O., Vaahtio M., Peltola T., Zhang D., Hupa L., Hupa M., Ylänen H., Salonen J., Viljanen M., Eerola E. Antibacterial effect of bioactive glasses on clinically important anaerobic bacteria in vitro. J Mat Sci, Materials in Medicine, 2008 Feb, 19(2):547-551.
Munukka E., Leppäranta O., Korkeamäki M., Vaahtio M., Peltola T., Zhang D., Hupa L., Ylänen H., Salonen J., Viljanen M., Eerola E. Bactericidal effects of bioactive glasses on clinically important aerobic bacteria. J Mat Sci: Materials in Medicine, 2008, Jan: 19(1):27-32.
Stoor P., Söderling E., Grénman R. Interactions between the bioactive glass S53P4 and the atrophic rhinitis-associated micro-organism Klebsiella ozaenae. J Biomed Mat Res (Appl Biomat), 1999, Vol. 48(6):869-874.
Stoor P., Söderling E., Salonen J. Antibacterial effects of a bioactive glass paste on oral microorganisms. Acta Odontol Scand. 1998, Jun; 56(3):161-165.
Stoor P., Söderling E., Grénman R. Interactions between the frontal sinusitis-associated pathogen Haemophilus Influenzae and the bioactive glass S53P4. Bioceramics, 1995, Vol. 8: 253-258.